Work number - M 40 AWARDED
Presented State Institution "Kolomiychenko Institute of Otolaryngology of National Academy of Medical Sciences of Ukraine"
Authors:
Yaroslav Kizim – Ph.D., research assistant, State Institution "Kolomiychenko Institute of Otolaryngology of National Academy of Medical Sciences of Ukraine".
The aim of this work was to increase the effectiveness of diagnosis and treatment of patients with squamous cell carcinoma of the larynx stage I-II in association with laryngopharyngeal reflux.
The scientific novelty is that for the first time the frequency of laryngopharyngeal reflux in patients with stage I-II laryngeal cancer was studied using daily pH-monitoring and questionnaires based on modified visual-analog scales The Reflux Symptom Index and The Reflux Finding Score.
Features of the pathomorphological picture of squamous cell carcinoma of the larynx of stage I-II in association with laryngopharyngeal reflux were determined. Based on pathomorphological studies, it was found that laryngopharyngeal reflux is associated with the development of a chronic inflammatory process in the laryngeal mucosa and the stimulation of hyperplasia of the integumentary epithelium.
The application of the developed therapeutic and diagnostic algorithm for patients with squamous cell carcinoma of the larynx stage I-II in association with laryngopharyngeal reflux can increase the effectiveness of diagnosis and treatment by reducing the number of rela
Number of publications: 5 scientific articles (1 in English-language journals with an impact factor), 18 abstracts of reports at domestic and international conferences. The total number of references to publications of authors / h-index of work according to the databases is respectively: Web of Science - 0/0, Scopus - 0/0, Google Scholar - 3/2. Received 2 patents of Ukraine for a useful model.
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