Regenerative and cellular technologies in the treatment of injuries of the musculoskeletal system in military personnel

Work number - P 14 FILED

Presented State Institution "Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine"

Authors:
Doctor of Medical Sciences O.O. Kostrub; Doctor of Medical Sciences R.I. Blonskyi; Doctor of biological sciences S. Magomedov; Doctor of Medical Sciences O.V. Dolgopolov; Doctor of Medical Sciences M.P. Grytsai; Candidate of Medical Sciences I.A. Zasadnyuk; Candidate of biological sciences D.O. Zubov; Doctor of Philosophy V.O. Rohozynskyi

The research methods include clinical, radiological, sonographic, arthroscopic, laboratory, histomorphological, fluorescent microscopy, and analytical-statistical methods.

This work addresses a current scientific and medical issue treating musculoskeletal injuries, particularly injuries to joint cartilage, tendons, bones, and ischemic muscles in military personnel using regenerative and cellular technologies. The experimental study deepened knowledge and demonstrated the positive therapeutic effects of mesenchymal stem cells, autologous fibroblasts, and autologous platelet-rich plasma on the regenerative processes in musculoskeletal injuries in experimental animals, with subsequent implementation of the results in the treatment of military personnel.

Differentiated approaches to treating joint cartilage, tendon, bone, and ischemic muscle injuries in military personnel using cellular and regenerative technologies, both alone and in combination with other, including surgical, treatment methods, were developed. This allowed for improved treatment outcomes and accelerated the return of military personnel to their professional activities, addressing a primary objective of military medicine.

The study materials are presented in 94 scientific works, including 9 patents, 4 monographs, 60 articles in professional journals listed by the Higher Attestation Commission of Ukraine or indexed in international databases, and 21 abstracts in the materials of scientific and practical conferences.

Number of publications: 26 reports at various scientific and practical conferences, and 2 innovations have been introduced. The practical implementation of the results is confirmed by 8 implementation acts. The novelty of the presented results meets international standards. One doctoral and two candidate dissertations have been defended. The total number of citations/h-index (citation index) of the authors' works according to scientometric databases is as follows: Web of Science – 139/5, Scopus – 222/7, and Google Scholar – 740/11

Name	Type	Size	File
Essay (Ukr.)	.pdf	1.12 MB	Download
Presentation of work	.pdf	4.15 MB	Download