Work number - M 22 FILED
Presented State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism of the National Academy of Medical Sciences of Ukraine»
Authors:
Ostafiychuk M. V.
To achieve the purpose of research in The Scientific and Practical Department of Orphan Endocrine Diseases and Endocrine Surgery of the State institution "V.P. Komisarenko Institute of Endocrinology and Metabolism of the National Academy of Medical Sciences of Ukraine", a cohort of patients was formed who were examined and operated in the Department of Endocrine Gland Surgery of the Institute during 2000-2023. Only patients with papillary carcinoma (PC) of the thyroid gland were included in the cohort, in whom the possibility of the presence of clinically occult lymph nodes was theoretically predicted at the preoperative stage, and after examination (including ultrasound and/or fine needle aspiration biopsy) no signs of possible metastasis to the neck lymph nodes were found (status N0). All patients underwent total thyroidectomy, if necessary combined with dissection of lymph nodes (central and/or lateral). The cohort included 566 patients aged 17-78, of whom 476 were women and 90 were men.
In order to solve the problems of the study, the data of patients who were part of both the complete created cohort and separate patients who made up its two subgroups were analyzed, namely: patients who underwent total thyroidectomy without prophylactic dissection of neck lymph nodes in the central group (346 patients), and patients who underwent prophylactic dissection of these lymph nodes simultaneously with total thyroidectomy (220 patients). In addition, the patients of the first subgroup were divided into three separate ones: patients in whom no metastases in the lymph nodes of the neck were detected during the operation and according to the data of the performed postoperative radioiodine ablation and the N0 tumor status remained. This group included 254 patients
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